How to Exercise Safely While Taking GLP-1 Medications
Exercise physiologists share evidence-based guidelines for maintaining an effective workout routine while on semaglutide or tirzepatide, including how to preserve muscle mass.

One of the most important considerations for patients on GLP-1 medications is maintaining muscle mass during weight loss. Research shows that without proper exercise, a significant portion of weight lost can come from lean muscle tissue rather than fat.
The Importance of Resistance Training
Resistance training is particularly important for patients on GLP-1 medications. Studies suggest that combining resistance exercise with GLP-1 therapy can help preserve lean muscle mass while maximizing fat loss.
Recommended Exercise Protocol
Exercise physiologists recommend a combination of resistance training (3-4 times per week) and moderate cardiovascular exercise (150 minutes per week) for optimal results. Patients should start gradually and increase intensity over time.



