Fitness & Exercise

    How to Exercise Safely While Taking GLP-1 Medications

    Exercise physiologists share evidence-based guidelines for maintaining an effective workout routine while on semaglutide or tirzepatide, including how to preserve muscle mass.

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    Dr. Michael Torres

    Sports medicine physician · February 8, 2025

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    How to Exercise Safely While Taking GLP-1 Medications

    One of the most important considerations for patients on GLP-1 medications is maintaining muscle mass during weight loss. Research shows that without proper exercise, a significant portion of weight lost can come from lean muscle tissue rather than fat.

    The Importance of Resistance Training

    Resistance training is particularly important for patients on GLP-1 medications. Studies suggest that combining resistance exercise with GLP-1 therapy can help preserve lean muscle mass while maximizing fat loss.

    Recommended Exercise Protocol

    Exercise physiologists recommend a combination of resistance training (3-4 times per week) and moderate cardiovascular exercise (150 minutes per week) for optimal results. Patients should start gradually and increase intensity over time.

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